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During the literature, we observed which the antimicrobial activity of benzofuran derivatives appears to be extra dependent on substitution at the heterocyclic furan ring than on substitution on the aromatic moiety.60 Telvekar and co-personnel investigated a number of benzofuran-3-carbohydrazide derivatives and screened for his or her likely antifu

No epidemiologic studies ended up located concerning the probable human carcinogenicity of 2,three-benzofuran. Life time oral publicity raises most cancers incidence in woman rats and in male and feminine mice (NTP 1989). The carcinogenicity in both sexes and both equally species, together with in several organs, strengthens the chance of a carcino